Tritium NMR spectroscopy of steroids

Abstract The 3 H NMR spectra of a series of 7 steroids tritiated at C(1), C(2), C(6), C(7), C(9) and C(16) yield quantitative information on the 3 H distribution in these compounds. Deuterated chloroform is not a good solvent to examine the regio‐ and stereospecificity of the labelling process for acid labile positions such as C(2) in a 3‐oxosteroid and C(6) in a 3‐oxo‐Δ 4 ‐steroid.