Expression of Matrix Metalloproteinases in Myocardium Contributes To Human Myocardial Remodeling during Atrial Fibrillation

In the recent study,the myocardial cells occur the structural change,extracellular matrix(ECM)ensure myocardial cellers normal location and integrated system.However,collegan is its main composition.Matrix Metalloproteinases(MMps) decompse collagen,which effect the change of myocardial structure,it is also the main factor of heart matrix composition during the remodelling.Extracellular matrix(ECM)also depends on the balance between the MMps and its inhibitor TIMPs.