Current Advances on the Extraction and Identification of Bioactive Components of Sage (Salvia spp.)

Common sage (Salvia spp., with the most common species Salvia officinalis L., Lamiaceae) is an important medicinal and aromatic plant, with antioxidant, antimicrobial, anti-inflammatory and anticancer properties. The polyphenolic compounds are mainly responsible for its diverse biological activity. Many different methods for extraction and identification of sage bioactive compounds, using various solvents, have been developed in recent years. The total phenolic content is usually measured and identified by various technical methodologies with different sensitivity and specificity. In this aspect, the present review is aimed to critically summarize and discuss various technical approaches for the extraction and identification of sage bioactive components in order to point out the more appropriate approaches of them.