化学
增强子
药理学
结构-活动关系
体外
生物化学
毛茛
细胞培养
生物物理学
化学合成
作者
Tao Zhang,Qh Zhang,Zhexin He,Yaoxuan Wang,Yanjie Wang,Jianyang Fang,Hongwu Liu,Liwei Hong,Y L Li,Xianzhong Zhang,Zhide Guo
标识
DOI:10.1021/acs.jmedchem.6c00613
摘要
Lu]Lu-PSMA-617, even at a reduced dose (9.25 MBq). High-tolerated dose studies (111 MBq) confirmed safety with unremarkable histopathology. These findings suggest that SNAC conjugation may represent a promising approach for the development of PSMA-targeted radiotheranostics for PCa.
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