化学
色谱法
指纹(计算)
高效液相色谱法
化学成分
颗粒(地质)
计算机科学
人工智能
地貌学
地质学
作者
Man‐Jiang Xie,Jie Wang,Chenguang Dong,Peng‐Fei Tu,Qingying Zhang
标识
DOI:10.1080/10826076.2023.2206667
摘要
Based on HPLC fingerprint analysis and multi-components quantification, a simple, sensible, and reliable HPLC-UV method, capable of qualitatively and quantitatively characterizing the main chemical markers of all medicinal herbs of Zaoren Anshen (ZRAS) prescription by one injection, was firstly developed. Then, three different dosage forms of ZRAS preparations, i.e., capsule, granule, and oral liquid, were analyzed and compared systematically, indicating the similarity and difference in chemical markers of the three ZRAS preparations. The strategy of combining HPLC chemical fingerprint and multi-components quantification in one injection was rather practical, powerful and useful in characterizing the main chemical markers of ZRAS preparations, which was a benefit for holistic quality evaluation and control of ZRAS preparations. Moreover, the present results provide sound scientific data for further studies on the effective constituents and quality control of ZRAS preparations.
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