A domino [3 + 2] cycloaddition/deamination/imine hydrolysis reaction of cyclopropyl spirooxindoles with thiourea for access to spiro-γ-thiolactone oxindoles

A Lu(OTf) 3 -catalyzed domino [3 + 2] cycloaddition/deamination/imine hydrolysis reaction of D–A cyclopropane with thiourea was developed to afford γ-thiolactone spirooxindoles.