Trace metals with heavy consequences on bees: A comprehensive review

The pervasiveness of human imprint on Earth is alarming and most animal species, including bees (Hymenoptera: Apoidea: Anthophila), must cope with several stressors. Recently, exposure to trace metals and metalloids (TMM) has drawn attention and has been suggested as a threat for bee populations. In this review, we aimed at bringing together all the studies (n = 59), both in laboratories and in natura, that assessed the effects of TMM on bees. After a brief comment on semantics, we listed the potential routes of exposure to soluble and insoluble (i.e. nanoparticle) TMM, and the threat posed by metallophyte plants. Then, we reviewed the studies that addressed whether bees could detect and avoid TMM in their environment, as well as the ways bee detoxify these xenobiotics. Afterwards, we listed the impacts TMM have on bees at the community, individual, physiological, histological and microbial levels. We discussed around the interspecific variations among bees, as well as around the simultaneous exposure to TMM. Finally, we highlighted that bees are likely exposed to TMM in combination or with other stressors, such as pesticides and parasites. Overall, we showed that most studies focussed on the domesticated western honey bee and mainly addressed lethal effects. Because TMM are widespread in the environment and have been shown to result in detrimental consequences, evaluating their lethal and sublethal effects on bees, including non-Apis species, warrants further investigations.