The clinical efficacy of percutaneous vertebroplasty combined with postural reduction versus kyphoplasty: A systematic review and meta-analysis

Background Osteoporotic vertebral compression fractures (OVCFs) are a significant cause of disability worldwide. Objective The purpose of this meta-analysis is to explore whether postural reduction and vertebroplasty (PRVP) offers the same therapeutic efficacy as KP to provide evidence for the treatment strategy of OVCFs. Methods We searched for the published results of relevant trials in PubMed (Jan 2000 to Dec 2023), Ovid (Jan 2000 to Dec 2023), Science Direct online (Jan 2000 to Dec 2023), the Cochrane Library, the Institute for Scientific Information (ISI) Web of Knowledge (Jan 2000 to Dec 2023), as well as several orthopaedics journals. The full text was obtained and reviewed for the studies meeting the inclusion and exclusion criteria. Results Five randomized studies were adequately included and analyzed. The data was pooled using Review Manager (REVMAN) 5.3 software. The pooled results showed no significant differences between the two groups in indicated outcomes: the Cobb's angle post-operation (MDs, 2.86; 95% CIs, −0.98 to 6.71; P = 0.14), leakage of cement during operation (RR, 1.66; 95% CIs, 0.89 to 3.08; P = 0.11) and the compression rate of related vertebra (MDs, 4.32; 95% CIs, −1.69 to 10.33; P = 0.16). Conclusion PRVP and KP were equally effective and safe in the clinical outcomes of OVCFs.