期刊:Oxford University Press eBooks [Oxford University Press] 日期:2011-04-21被引量:151
标识
DOI:10.1093/hesc/9780199569113.001.0001
摘要
Introduction to Glycobiology considers the impact of sugars on biological systems, explaining their function at the molecular, cellular, and organismal level. It is made up of two parts. Part 1 looks at the structures and biosynthesis of glycans and includes chapters that examine concepts of glycobiology, N-linked glycosylation, O-linked glycosylation, and glycolipids and membrane protein glycosylation. There are also chapters on enzymology and the cell biology of glycosylation, analysis of glycan structures, and conformations of oligosaccharides. Part 2 focuses on glycans in biology. This section looks at the following topics: the effects of glycosylation on protein structure and function; carbohydrate recognition in cell adhesion and signalling; glycoprotein trafficking in cells and organisms; glycobiology of plants, bacteria, and viruses; glycobiology and development; glycosylation and disease; and the future of glycobiology.