医学
结直肠癌
接收机工作特性
磁共振成像
病态的
淋巴血管侵犯
单变量分析
逻辑回归
曲线下面积
淋巴结转移
放射科
核医学
多元分析
内科学
转移
肿瘤科
癌症
作者
Mingzhu Zhou,Hong Huang,Yu Fan,Min Chen,Ming Li,Yuting Wang
标识
DOI:10.1016/j.crad.2023.10.027
摘要
Aim To investigate the diagnostic value of golden-angle radial sparse parallel magnetic resonance imaging (MRI) (GRASP) and R2* in predicting the prognostic factors of resectable rectal cancer. Materials And Methods A total of 108 patients with rectal adenocarcinoma were included in this retrospective study. The volume transfer constant (Ktrans), rate constant (Kep), plasma volume fraction (Ve), and R2* were obtained. Univariate and multivariate logistic regression were conducted. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of the imaging parameters. Results The Ktrans was found to be significantly higher in rectal cancers with positive lymph node metastasis (LNM), higher tumour grade, positive lymphovascular invasion (LVI), and higher ki-67 (all p<0.05). The Kep was also significantly higher in the LNM-positive group (p<0.001), while the R2* was higher in rectal cancers with LNM-positive, higher tumour grade, LVI-positive, and higher ki-67 (all p<0.05). Combining the Ktrans and R2* provided the highest area under the ROC curve (AUC) for LNM-positive and higher ki-67 tumours differentiation (0.790 and 0.823, respectively). Discussion Combining quantitative parameters of the Ktrans and R2* could be used to non-invasively predict pathological prognostic factors preoperatively.
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