Synthesis of N-fused polycyclic indoles via a Pd-catalyzed multicomponent cascade reaction consisting of an amide-directed [3+1+1] annulation reaction of 3-diazo oxindole and isocyanides

A palladium-catalyzed and amide-assisted multicomponent reaction of 3-diazo oxindole, isocyanide, and water to generate biologically important oxazole-fused indole scaffolds has been reported.