肝损伤
巨噬细胞极化
Notch信号通路
细胞生物学
癌症研究
信号转导
M2巨噬细胞
促炎细胞因子
下调和上调
免疫学
生物
巨噬细胞
炎症
内分泌学
生物化学
体外
基因
作者
Yan Yang,Ming Ni,Ruobin Zong,Mengxue Yu,Yishuang Sun,Jiahui Li,Pu Chen,Changyong Li
标识
DOI:10.1016/j.jcmgh.2023.01.002
摘要
Our findings underscore a novel molecular insight into the Notch1-YAP circuit for controlling macrophage polarization in acute liver injury, raising the possibility of targeting macrophage Notch1-YAP circuit as an effective strategy for liver inflammation-related diseases.
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