An Active Lifestyle Prior to Coronary Surgery Is Associated With Improved Survival in Elderly Patients

医学 旁路移植 内科学 比例危险模型 体力活动 心脏病学 生存分析 冠状动脉疾病 对数秩检验 心脏外科 代谢当量 动脉 物理疗法
作者
Giuseppe Rengo,Gennaro Galasso,Dino Franco Vitale,Giuseppe Furgi,Carmela Zincarelli,Luca Golino,Grazia Daniela Femminella,Federico Piscione,F. Rengo,Dario Leosco
出处
期刊:The Journals of Gerontology [Oxford University Press]
卷期号:65A (7): 758-763 被引量:16
标识
DOI:10.1093/gerona/glp216
摘要

An active lifestyle is associated with a reduced cardiovascular risk in middle-aged as well as in elderly patients. In the present study, we investigated the association between physical activity habits of elderly participants prior to coronary artery bypass grafting (CABG) and survival free from both all-cause and cardiac death.Study population consisted of 587 elderly patients (>or=70 years) CABG patients stratified, according to the Physical Activity Scale for the Elderly (PASE), into less active (low PASE) and exercised (high PASE) groups. At follow-up (mean: 44.3 +/- 21.0 months), 33 (37.1%) of 89 total deaths occurred for cardiac causes. Sixty-month survival rate was 65% and 96% for low-PASE and high-PASE groups, respectively (log rank = 49.460, p < .0001). Cox survival analysis indicated a significant (p < .0001) nonlinear association between PASE score increments and improved survival with the most evident differences in the lowest score categories. A robust association was also found between low PASE score and increased cardiac-related mortality (p < .0001).Our data indicate that a more active lifestyle is significantly associated with improved survival in elderly CABG patients. The nonlinearity of the relation suggests that more sedentary patients could have the most benefit on survival by increasing their exercise lifestyle habits. The improved outcome is explained by both cardiac and overall mortality reduction.

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