Study on the relationship between blood cell parameters and short- term major adverse cardiovascular events( MACE) in patients with acute myocardial infarction

Objective To analyze the rule of changes in red cell parameters of patients in short term after the onset of acute myocardial infarction,and to study the relationship between red blood cell volume distribution width( RDW) and shortterm major adverse cardiovascular events( MACE). Methods A total of 100 patients with acute myocardial infarction diagnosed in this hospital were allocated in this study,blood routine examinations at 1st to 4th d,5th to 8th d and 9th to 12th d after myocardial infarction were detected for realization of changes in red blood cell parameters after infarction. They were divided into positive group( 43 cases) and negative group( 57 cases) after admission according to the occurrence of MACE or not,the difference in RDW was compared between these 2 groups. Results At 5th to 8th d after acute myocardial infarction,levels of RBC count,HB and HCT showed a trend of gradual decline,the difference was statistically significant( P 0. 05). The levels of MCV and MCH were gradually increased( P 0. 05); concentration of MCH had a gradually decreased trend( P 0. 05); RDW was increased from 1st to 4th d,and it reached peak at 5th to 8th d,and it gradually declined from 9th to 12th d( P 0. 05). The difference in RDW between MACE positive group and MACE negative group was significant( P 0. 01). Conclusion ①After acute myocardial infarction,RDW is significantly increased,it is suggested that it may closely be related to the occurrence of shortterm major adverse cardiovascular events in patients with acute myocardial infarction. ②Following the continuous progress of acute myocardial infarction,the levels of red blood cells,hemoglobin etc parameters are decreased,and other morphological parameters are also accordingly changed.