Sedative effect of dexmedetomidine on patients with Cerebral Lesions in ICU

Objective To observe the sedative effect of dexmedetomidine on the patients with Cerebral Lesions in ICU.Methods Dexmedetomidine is given by continuous infusion following a load dose to provide satifactory sedation in 50 patients with Cerebral Lesions.Maintain Ramsay score 2 ～ 5 points.Results The sedation efficiency was(86.6 ± 7.3) %.The average infusion rate of midazolam during the sedative period was (0.52 +0.13) μg/(kg·h),while the signs of life remained stable.Conclusion Dexmedetomidine can provide satisfactory sedation and unique advantage for ICU patients.