Influence of lipid peroxidation and anti-lipid peroxidation in the area of high water arsenic

Objective To study the effect of high arsenic water on lipid peroxidation and anti-lipid peroxidation for clarifying the danger and the pathogenetic mechanism. Methods The SOD, GSH-Px, GSH and LPO of different age groups were measured and analysed. Results The higher the level of water arsenic, the higher the activity of SOD in serum was, especially in the 36 to 55 age groups, but the LPO level was significantly lower than the control group(P 0.05). The GSH level was higher than that in higher water arsenic area (P 0.05). The activity of GSH-Px 55 in age control group of 55 and above was higher than high water arsenic area. Conclusions Drinking high water arsenic could affect the system of lipid peroxidation and anti-lipid peroxidation, causing lipid peroxidation and damage to the body and compensative increase of anti-lipid peroxidation.