An Experimental Study on Rhizoma Corydalis Processed with Different Acid

Objective:To probe the effects of Rhizoma Corydalis processed with different acids on both the content of tetrahydropalmatine and the analgesia by Rhizoma Corydalis.Method: The decoction amount of the tetra-hydropalmatine was measured by HPLC.The pain threshold was measured separately before and after mice took the drug by means of the hot plate.Result: The different processing of Rhizoma Corydalis exerted a certain influence on the decoction amount of the tetrahydropalmatine.Rhizoma Corydalis and its different acid products had an analgesic effect on the mice causing pain by hot plate.Conclusion: Of all the acid products of Rhizoma Corydalis,acetic acid ones had the least satisfactory effect.The comparison between malic acid,hydrochloric acid products and ace-tic acid product was not clearly marked.The citric acid products and the tartaric acid products had a certain advan-tage over others.