Synthesis of telmisartan

Objective:To synthesize telmisartan.Method:Telmisartan was prepared form 2-n-propyl-4-methyl-6-(methoxycarbonyl) benzimidazole by a 3-step process of cyclization,condensation,and hydrolysis.Results:The total yield of telmisartan was 45.6%.Conclusion:The method increases telmisartan yield,simplifies its process and decreases the cost.