Clonorchis sinensis parasitises in the bile ducts of human and dogs,cats and other animals.Clonorchiasis is a serious zoonotic parasitic disease causing a series of liver and gallbladder disease.So choosing fast and accurate diagnostic way of treatment is important to prevent and cure the disease.Nowadays,immunological detection has been widely used in the diagnosis of clonorchiasis. This paper provides an overview on research progress in ways of immunological detection of clonorchiasis.