医学
超声波
卵巢癌
放射科
恶性肿瘤
金标准(测试)
腹腔镜检查
癌症
内科学
作者
Maria Cristina Moruzzi,G. Bolomini,Francesca Moro,F. Mascilini,Silvia Ficarelli,Giuliana Beneduce,Maria Teresa Giudice,Tina Pasciuto,Rossana Moroni,Giovanni Scambia,Anna Fagotti,Antonia Carla Testa
出处
期刊:International Journal of Gynecological Cancer
[BMJ]
日期:2020-09-07
卷期号:31 (2): 279-285
被引量:2
标识
DOI:10.1136/ijgc-2020-001606
摘要
A radical surgical approach represents the mainstay treatment for gynecological malignancy, and preoperative staging of ovarian cancer is crucial. Ultrasound evaluation is widely recognized as the gold standard technique for the characterization of ovarian masses due to a high sensitivity for malignancy. In addition, its accuracy in defining intra-abdominal ovarian cancer spread has been previously proposed.To analyze the agreement between preoperative ultrasound examination and laparoscopic findings in assessing the extension of intra-abdominal disease using six parameters as described by Fagotti's score.When performed by expert examiners, ultrasound can be an accurate technique to assess tumor spread in ovarian cancer and therefore to predict surgical resectability.This is a single-center prospective observational study. Patients with clinical and/or radiological suspicion of advanced ovarian or peritoneal cancer will be assessed with preoperative ultrasound and assigned a score based on the six Fagotti's laparoscopic score parameters. Each parameter will then be correlated with laparoscopic findings.Eligible patients include women 18-75 years of age with clinical and/or imaging suggestive of advanced ovarian or peritoneal cancer, and an ECOG performance status 0-3.Sensitivity and specificity of ultrasound in detecting carcinomatosis, using the parameters of Fagotti's score as a reference standard. Agreement between preoperative ultrasound examination and laparoscopic findings in assessing the extension of intra-abdominal disease as described in Fagotti's score.240 patients.The accrual started in January 2019. Enrollment should be completed approximately by October 2020 and the results will be analyzed by December 2020.The study received the Ethical Committee approval on July 19 2018 (Protocol 28967/18 ID:2172).
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