Surgical treatment aimed at excising necrotic tissues, followed by covering of the non-epithelized surface with biological material is an essential component of a package of medical measures in ocular burn injury. This investigation was undertaken to reveal causal effects of the development of complications and to determine the efficiency of a silicone-dried Flexamer amniotic membrane used in the surgical treatment of ocular burn injury. The results of treatment in 76 patients with severe and very severe bum injury have shown that delayed epithelial recovery is a determinant of the development of complications typical of ocular burn injury. Necrectomy and covering of a silicone-dried Flexamer amniotic membrane, performed not later than 14 days after burn injury are the methods of choice in creating the conditions for regeneration of the epithelial surface of the eyeball and in diminishing the poor outcomes of treatment for sequels of ocular burn injury.