The small peptide VISP1 acts as a selective autophagy receptor regulating plant-virus interactions

ABSTRACTSelective macroautophagy/autophagy is tightly regulated by cargo receptors that recruit specific substrates to the ATG8-family proteins for autophagic degradation. Therefore, identification of selective receptors and their new cargoes will improve our understanding of selective autophagy functions in plant development and stress responses. We have recently demonstrated that the small peptide VISP1 acts as a selective autophagy receptor to mediate degradation of suppressors of RNA silencing (VSRs) of several RNA and DNA viruses. Moreover, VISP1 induces symptom recovery through fine-tuning the balance of plant immunity and virus pathogenicity. Our findings provide new insights into the double-edged sword roles of selective autophagy in plant-virus interactions.KEYWORDS: plant-virus interactionsreceptorselective autophagysmall peptidessuppressors of RNA silencing Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThe work was supported by Chinese Universities Scientific Fund (2023TC154) and Special funds for guiding the construction of world-class universities (disciplines) and characteristic development in central universities.