免疫系统
生物
计算生物学
信号转导
免疫失调
神经科学
突变
表型
破译
医学
蛋白质-蛋白质相互作用
机制(生物学)
细胞信号
HEK 293细胞
细胞生物学
遗传学
作者
Zhaolong Yu,Songzhi Jin,Shubo Wan,Zixuan Zhang,Yingjie Jiang,Jialin Li,Suzhen Wu
标识
DOI:10.1080/08820139.2025.2596074
摘要
As a critical GEF, DOCK2 plays a central role in immune and non-immune cellular processes through Rac and non-Rac signaling pathways. Dysregulation of DOCK2 is closely associated with multiple diseases. Further elucidation of its regulatory networks may reveal novel therapeutic targets for treating related disorders.
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