化学
烟酰胺磷酸核糖转移酶
阻塞(统计)
烟酰胺
生物化学
NAD+激酶
酶
计算机科学
计算机网络
作者
Tiangong Lu,Fangfang Chen,Jianhua Yao,Zhaode Bu,Anahita Kyani,Benji Liang,Shaoting Chen,Yu Zheng,Hong Liang,Nouri Neamati,Yanghan Liu
标识
DOI:10.1021/acs.jmedchem.4c00193
摘要
Nicotinamide phosphoribosyltransferase (NAMPT) is an attractive therapeutic target for treating select cancers. There are two forms of NAMPT: intracellular NAMPT (iNAMPT, the rate-limiting enzyme in the mammalian NAD
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