Retrospective analysis of the clinical efficacy of BuzhongQingli decoction in immunoglobulin A nephropathy exhibiting the dampness-heat due to spleen deficiency syndrome

To investigate the effect of BuzhongQingli Decoction (BZQLT) on the symptoms, hematuria, proteinuria, serum creatinine (SCr) of patients with immunoglobulin A nephropathy (IgAN), exhibiting the dampness-heat due to spleen deficiency syndrome. Methods: Patients with IgAN who were treated with BZQLD over a three-month period between 2022 and 2023, were enrolled in this study. Data collected included TCM syndrome scores, urine red blood cell count/HP, 24-hour urinary protein quantification (24-UTP), SCr before and after treatment. Results:Treatment with BZQLD over three months led to significant reductions in TCM syndrome scores, urine red blood cell count/HP, 24-UTP, and SCr levels in 62 patients. Conclusion: BZQLD effectively reduces the TCM syndrome scores and improves key clinical efficacy indicators in patients with IgAN presenting with the dampness-heat due to spleen deficiency syndrome, demonstrating its substantial clinical efficacy