腙
化学战剂
塔邦
沙林
化学
化学战
组合化学
肉眼
比色法
软件可移植性
硫芥
选择性
检出限
色谱法
有机化学
计算机科学
生化工程
毒性
程序设计语言
政治学
法学
工程类
乙酰胆碱酯酶
酶
催化作用
作者
Lucile Termeau,Sébastien Penlou,Alexandre Carella
出处
期刊:ACS Sensors
[American Chemical Society]
日期:2023-04-10
卷期号:8 (4): 1510-1517
被引量:3
标识
DOI:10.1021/acssensors.2c02505
摘要
Novichok is a recently identified class of neurotoxic organophosphorus compounds that have subsequently been banned by the Organization for Prohibition of Chemical Weapons (OPCW) as chemical warfare agents. Selective, rapid detection of Novichok remains a challenge. Several colorimetric paper-based detection devices have recently been developed for the rapid and selective detection of sarin, VX, and sulfur mustard. In this article, we present a similar colorimetric device designed specifically for the detection of Novichok, based on hydrazone derivatives from 2,4-dinitrophenylhydrazine (2,4-DNPH) impregnated on a glass fiber substrate. Results show that these compounds rapidly and selectively reveal the presence of Novichok agents to the naked eye. The low cost, ease of use, portability, and high selectivity to Novichok of this device complete the detection range of colorimetric paper-based sensors for chemical warfare agents.
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