Access to thiazoles via [3 + 2] cycloaddition of 1,2,3-thiadiazoles with isonitriles

The formal [3 + 2] cycloaddition of 1,2,3-thiadiazoles with isonitriles is developed to access structurally diverse 4,5-disubstituted thiazoles, in which the thioketene as a sulfo-2C-synthon is first disclosed.