Effects of washing of the face with a mild facial cleanser formulated with sodium laureth carboxylate and alkyl carboxylates on acne in Japanese adult males

清洁剂 痤疮 刺激 皮肤病科 皮肤刺激 角质层 医学 皮肤护理 苯佐卡因 红斑 洗剂 化妆品 麻醉 药理学 病理 护理部 免疫学
作者
K Isoda,Yutaka Takagi,K Endo,Masahiro Miyaki,Kazuya Matsuo,Koji Umeda,Kumi Umeda‐Togami,Hitoshi Mizutani
出处
期刊:Skin Research and Technology [Wiley]
卷期号:21 (2): 247-253 被引量:17
标识
DOI:10.1111/srt.12183
摘要

BACKGROUND/PURPOSE: Washing the face with a mild cleanser is generally recommended for acne care. Occasionally, the general public has the misconception that acne is exacerbated by cleansers and furthermore it has concerns about inducing skin irritation and xerosis by intensive washing. Recently, we developed a new cleanser based on sodium laureth carboxylate and alkyl carboxylates (AEC/soap) that cleans sebum well without penetrating the stratum corneum. METHODS: We designed a controlled clinical trial conducted on adult Japanese males with moderate or less acne. Twenty subjects washed their faces with AEC/soap base cleanser twice a day for 4 weeks. Assessment of the efficacy was conducted prior to the start of the study, and at the end of weeks 2 and 4. RESULTS: Significant improvement of the acne was observed within 2 weeks, and acne lesions were not detectable in 25% of the subjects at week 4. Sebum secretion levels on the skin significantly increased on the forehead, but significantly decreased on the cheek which correlated with the improvement. No complaints of dryness or irritation occurred during the study. CONCLUSION: Washing the face twice a day with facial cleanser based on AEC/soap is an effective care for moderate or less grade facial acne.
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