丙烯酰胺
中国人口
检出限
毒理
化学
人口
食品科学
健康风险
食物消费
色谱法
生物
环境卫生
医学
有机化学
经济
聚合物
基因型
共聚物
基因
生物化学
农业经济学
作者
F. Chen,Ye Yuan,Jianfeng Liu,Guanglu Zhao,Xiao Hu
标识
DOI:10.1080/02652030802512461
摘要
A survey of levels of acrylamide (AA) in 349 food products obtained from the Chinese market was conducted. AA was determined by an liquid chromatography-tandem mass spectrometry (LC-MS/MS) method. The limit of detection (LOD) and the limit of quantification (LOQ) of the method in four different matrices ranged from 0.8 to 10 µg kg(-1) and from 4.0 to 25 µg kg(-1), respectively. The results from this survey indicated that AA was present in all samples except drinking water and tea. AA contents in different samples varied greatly according to the raw materials and processing conditions. The highest level of AA was found in potato products, with an average level of 1467 µg kg(-1). Preliminary estimates of AA exposure and risk assessment of AA from foods in the Chinese population were performed using a combination of data obtained in the present survey and 2002 dietary consumption survey carried out in 2002 for the Chinese population. The average dietary exposure of AA was estimated to be 0.38 µg kg(-1) body weight day(-1), which is relatively low compared with the result reported by the Food and Agricultural Organization/World Health Organization (FAO/WHO). Furthermore, the margin of exposure for neurotoxicity, reproductive toxicity, and carcinogenicity of AA was calculated to be 1318, 5250, and 787, respectively.
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