Research Progress in Dopamine and Norepinephrine for the Treatment of Septic Shock

Septic shock is a complex clinical syndrome with a high mortality,as one the of most frequent causes of intensive care unit deaths that seriously threaten human health.Dopamine and norepinephrine can be used as the first-line hypertensive agents due to their remarkable effects on kidney and other organs,whereas dopamine has a more significant tachycardiac effect than norepinephrine.In the treatment of septic shock,early diagnosis and identification of mortality-associated risk factors are required,including more evidence-based medicine involvement.Appropriate and potent management in attempt to maximize the rescue rate of septic shock is critical for the minimization of mortality.