A Focus on Enterochromaffin Cells among the Enteroendocrine Cells: Localization, Morphology, and Role

嗜铬细胞 肠内分泌细胞 生物 分泌物 细胞生物学 血清素 运动性 内分泌系统 内分泌学 生物化学 受体 激素
作者
Rita Rezzani,Caterina Franco,Lorenzo Franceschetti,Marzia Gianò,Gaia Favero
出处
期刊:International Journal of Molecular Sciences [Multidisciplinary Digital Publishing Institute]
卷期号:23 (7): 3758-3758 被引量:25
标识
DOI:10.3390/ijms23073758
摘要

The intestinal epithelium plays a key role in managing the relationship with the environment, the internal and external inputs, and their changes. One percent of the gut epithelium is represented by the enteroendocrine cells. Among the enteroendocrine cells, a group of specific cells characterized by the presence of yellow granules, the enterochromaffin cells, has been identified. These granules contain many secretion products. Studies showed that these cells are involved in gastrointestinal inflammatory conditions and hyperalgesia; their number increases in these conditions both in affected and not-affected zones of the gut. Moreover, they are involved in the preservation and modulation of the intestinal function and motility, and they sense metabolic–nutritional alterations. Sometimes, they are confused or mixed with other enteroendocrine cells, and it is difficult to define their activity. However, it is known that they change their functions during diseases; they increased in number, but their involvement is related mainly to some secretion products (serotonin, melatonin, substance P). The mechanisms linked to these alterations are not well investigated. Herein, we provide an up-to-date highlight of the main findings about these cells, from their discovery to today. We emphasized their origin, morphology, and their link with diet to better evaluate their role for preventing or treating metabolic disorders considering that these diseases are currently a public health burden.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
icing完成签到,获得积分10
1秒前
2秒前
3秒前
唐泽雪穗应助科研通管家采纳,获得10
3秒前
科研通AI2S应助科研通管家采纳,获得10
3秒前
科目三应助科研通管家采纳,获得10
4秒前
fifteen应助科研通管家采纳,获得10
4秒前
jackten发布了新的文献求助10
4秒前
科研通AI5应助科研通管家采纳,获得10
4秒前
天天快乐应助科研通管家采纳,获得10
4秒前
乐乐应助科研通管家采纳,获得10
4秒前
FashionBoy应助科研通管家采纳,获得10
4秒前
完美世界应助科研通管家采纳,获得10
4秒前
SciGPT应助科研通管家采纳,获得10
4秒前
Akim应助科研通管家采纳,获得10
4秒前
我是老大应助科研通管家采纳,获得10
4秒前
5秒前
唐泽雪穗应助科研通管家采纳,获得10
5秒前
5秒前
芋头完成签到,获得积分10
6秒前
7秒前
8秒前
斐波拉切土豆完成签到 ,获得积分10
8秒前
9秒前
刘杰青发布了新的文献求助30
10秒前
qweqwe完成签到 ,获得积分10
10秒前
斯文败类应助菠萝派采纳,获得10
11秒前
11秒前
GealAntS完成签到,获得积分0
11秒前
DreamMaker发布了新的文献求助10
12秒前
13秒前
Esperanza完成签到,获得积分10
13秒前
谢慧蕴应助zhdjj采纳,获得10
13秒前
哈哈哈哈哈哈鹅完成签到,获得积分10
14秒前
16秒前
16秒前
17秒前
Yingkun_Xu发布了新的文献求助10
17秒前
18秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
高温高圧下融剤法によるダイヤモンド単結晶の育成と不純物の評価 5000
苏州地下水中新污染物及其转化产物的非靶向筛查 500
Rapid Review of Electrodiagnostic and Neuromuscular Medicine: A Must-Have Reference for Neurologists and Physiatrists 500
Vertebrate Palaeontology, 5th Edition 500
ISO/IEC 24760-1:2025 Information security, cybersecurity and privacy protection — A framework for identity management 500
碳捕捉技术能效评价方法 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 内科学 生物化学 物理 计算机科学 纳米技术 遗传学 基因 复合材料 化学工程 物理化学 病理 催化作用 免疫学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 4727442
求助须知:如何正确求助?哪些是违规求助? 4084047
关于积分的说明 12631452
捐赠科研通 3790710
什么是DOI,文献DOI怎么找? 2093421
邀请新用户注册赠送积分活动 1119233
科研通“疑难数据库(出版商)”最低求助积分说明 995469