小RNA
子痫
滋养层
生物标志物
生物
缺氧(环境)
计算生物学
基因
生物信息学
怀孕
遗传学
胎盘
胎儿
化学
有机化学
氧气
作者
Ilona Jaszczuk,Dorota Koczkodaj,Adrianna Kondracka,Anna Kwaśniewska,Izabela Winkler,Agata Filip
标识
DOI:10.1080/07853890.2022.2071459
摘要
MicroRNAs (miRNAs) are a class of small non-coding, single-stranded RNAs (ribonucleic acids) that play important roles in many vital processes through their impact on gene expression. One such miRNA, miR210, represents a hypoxia-induced cellular miRNA group that hold a variety of functions. This review article highlights the importance of miR-210 in the development of pre-eclampsia.KEY MESSAGEmiR-210 is a promising biomarker for monitoring pregnancy with pre-eclampsia. Overexpression of miR-210 had a negative impact on the process of cell migration and trophoblast invasion.
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