医学
哮喘
重症监护医学
疾病
梅德林
气道
生活质量(医疗保健)
呼吸道疾病
免疫学
临床试验
肾上腺素能β激动剂
内科学
生物制剂
急性重症哮喘
奥马佐单抗
支气管扩张药
吸入性皮质类固醇
作者
Guy G. Brusselle,Gerard H. Koppelman
标识
DOI:10.1056/nejmra2032506
摘要
Patients with severe asthma are at increased risk for a decreased quality of life, fixed airway obstruction, hospitalization, and death. Biologics may be required to reduce the disease burden. This review discusses the mechanisms, efficacy, and safety of biologics for severe asthma.
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