片段(逻辑)
杀虫剂
多样性(控制论)
机制(生物学)
三氟甲基
化学
计算机科学
生物
生态学
人工智能
有机化学
哲学
认识论
程序设计语言
烷基
作者
Zhiguo Zheng,Ali Dai,Zhichao Jin,Yonggui Robin,Jian Wu
标识
DOI:10.1021/acs.jafc.1c08383
摘要
Trifluoromethylpyridine (TFMP) is a biologically active fragment formed by connecting trifluoromethyl and pyridine ring. As a result of its unique physical and chemical properties and outstanding biological activity, a variety of pesticide compounds with the TFMP fragment have been discovered and marketed and have played important roles in crop protection research. It is therefore a timely and valuable task to summarize the rationality on how to create new molecules containing TFMP fragments based on the structure-activity relationships, design mentality, and potential mechanism. This review gives a brief summary on the pesticides containing TFMP fragments in the past 5 years and introduces the latest progress of our group in this field. The aim is to provide readers with a convenient route to touch this topic and hopefully serve some educational purpose for graduate students as well.
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