白杨素
生物利用度
药理学
化学
抗氧化剂
广谱
多酚
医学
类黄酮
生物化学
组合化学
作者
Shreya Chitrakant Adangale,Sarika Wairkar
出处
期刊:Food bioscience
[Elsevier]
日期:2022-02-01
卷期号:45: 101316-101316
被引量:10
标识
DOI:10.1016/j.fbio.2021.101316
摘要
Flavonoids are a diverse group of phytonutrients that have gained attention as dietary supplements due to their broad spectrum of therapeutic properties and negligible side effects. Chrysin, a 5,7-dihydroxyflavone, has been explored for various pharmacological effects in the last few decades. Despite vast biological activities, the use of this polyphenol seems to be compromised due to low solubility, extensive pre-systemic metabolism and thus very poor oral bioavailability. The present review elucidates various pharmacological actions of chrysin such as cardioprotective, antioxidant, neuroprotective, hepatoprotective, anti-inflammatory, anticancer and antidiabetic activities with the help of reported scientific studies. Additionally, it focuses on different formulations developed for chrysin to increase its absorption and subsequent bioavailability. This review thus analyses the beneficial effects of chrysin and gives an overview of possible techniques adopted to increase its systemic bioavailability.
科研通智能强力驱动
Strongly Powered by AbleSci AI