Norwilsonnol A, an immunosuppressive polycyclic polyprenylated acylphloroglucinol with a spiro[5-oxatricyclo[6.4.0.03,7]dodecane-6′,1-1′,2′-dioxane] system from Hypericum wilsonii

Norwilsonnol A (1), a structurally complex polycyclic polyprenylated acylphloroglucinol (PPAP) bearing an unprecedented scaffold, together with a new biosynthetic analogue, norwilsonnol B (2), were isolated from Hypericum wilsonii.