医学
心脏病学
内科学
无症状的
亚临床感染
射血分数
糖尿病性心肌病
糖尿病
径向应力
斑点追踪超声心动图
2型糖尿病
心肌病
心力衰竭
内分泌学
有限元法
物理
热力学
作者
Laura Ernande,Ernst Rietzschel,Cyrille Bergerot,Marc L. De Buyzere,Frédéric Schnell,L. Groisne,Michel Ovize,Pierre Croisille,Philippe Moulin,Thierry C. Gillebert,Geneviève Dérumeaux
标识
DOI:10.1016/j.echo.2010.09.007
摘要
Diabetic cardiomyopathy has been characterized by an early impairment of left ventricular (LV) longitudinal function as opposed to preserved LV radial function.Conventional echocardiography and longitudinal (ε(L)) and radial (ε(R)) systolic strain assessed by speckle-tracking imaging were obtained in 114 type 2 diabetic patients and 88 age-matched controls.LV ejection fraction was similar in diabetic patients and controls. The presence of subclinical LV systolic dysfunction in diabetic patients was demonstrated by lower values of midwall fractional shortening (18% ± 3% vs 20% ± 3%, P = .006), ε(L) (-19% ± 3% vs -22% ± 2%, P < .001), and ε(R) (50% ± 16% vs 56% ± 12%, P = .003) compared with controls. On multivariate analysis, factors predicting strain values were diabetes (P = .001) and gender (P = .001) for ε(L) and diabetes (P = .003) for ε(R).Diabetic patients without overt heart disease display subclinical alteration of both radial and longitudinal LV systolic function even after adjustment for blood pressure, age, and body mass index.
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