光热治疗
脂肪组织
细胞
光动力疗法
光热效应
脂解
细胞膜
组织工程
材料科学
生物物理学
化学
生物医学工程
生物化学
纳米技术
生物
医学
有机化学
作者
Valery V. Tuchin,Irina Yu. Yanina,Georgy V. Simonenko
摘要
Destructive fat tissue engineering could be realized using the optical method, which provides reduction of regional or site-specific accumulations of subcutaneous adipose tissue on the cell level. We hypothesize that light irradiation due to photodynamic and selective photothermal effects may lead to fat cell lypolytic activity (the enhancement of lipolysis of cell triglycerides due to expression of lipase activity and cell release of free fat acids (FFAs) due to temporal cell membrane porosity), and cell delayed killing due to apoptosis caused by the induced fat cell stress and/or limited cell necrosis.
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