Endopiriform nucleus connectivities: the implications for epileptogenesis and epilepsy.

Several anterograde and retrograde tracing studies have provided detailed information on the afferent and efferent projections as well as the intrinsic connectivities of the endopiriform nucleus (EN). Here, we summarise EN connectional data and the principles of their organisation and discuss the role they may play in the development and spread of epileptic seizures.