Interventional therapy by bronchuscope on trachea adenoid cystic carcinoma in end stage

Objective To evaluate clinical curative effect and complications of different interventional methods by bronchoscopy on trachea adenoid cystic carcinoma (TACC).Methods The data of 25 patients with TACC in Meitan general hospital from January 2008 to October 2012 were retrospectively analyzed.The trachea diameter and dyspnea index were compared before and after treatment.Results The symptoms of all patients were improved after treatment.The trachea diameter increased significantly from (5.6± 1.6) mm to (13.2± 1.5) mm (P ＜0.01),and the dyspnea index decreased dramatically from 2.8±0.8 to 1.7±0.5 (P ＜0.01).Cough,haemoptysis,pharynx pain were the general complications following treatments.Trachea restenosis due to tumor relapse was major longterm complication.The incidence of trachea restenosis in 125Ⅰ radioactive seed implantation group was lower compared with the other groups during one month and three months follow-up.Conclusions The signs and symptoms were improved with different interventional methods by bronchoscopy in patients with TACC.The incidence of trachea restenosis may be low when patients receiving argon plasma coagulation,CO2 cryosurgery and 125Ⅰ radioactive seed implantation. Key words: Trachea adenoid cystic carcinoma;  Bronchoscope;  Interventional therapy; 125Ⅰ radioactive seed ;  Complication