微泡
骨愈合
背景(考古学)
外体
血管生成
细胞外小泡
细胞生物学
伤口愈合
过程(计算)
医学
生物
计算机科学
免疫学
癌症研究
小RNA
解剖
古生物学
生物化学
基因
操作系统
作者
Shihong Lv,G WANG,Liuliu Dai,T WANG,Feng Wang
出处
期刊:Physiological Research
[Institute of Physiology of the Czech Academy of Sciences]
日期:2023-11-20
卷期号:72 (5): 565-574
被引量:1
标识
DOI:10.33549/physiolres.935143
摘要
Fracture healing is a multifaceted process that requires various phases and intercellular interactions. In recent years, investigations have been conducted to assess the feasibility of utilizing exosomes, small extracellular vesicles (EVs), to enhance and accelerate the healing process. Exosomes serve as a cargo transport platform, facilitating intercellular communication, promoting the presentation of antigens to dendritic cells, and stimulating angiogenesis. Exosomes have a special structure that gives them a special function, especially in the healing process of bone injuries. This article provides an overview of cellular and molecular processes associated with bone fracture healing, as well as a survey of existing exosome research in this context. We also discuss the potential use of exosomes in fracture healing, as well as the obstacles that must be overcome to make this a viable clinical practice.
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