The Yb@g-C3N4 Dual-Functional Photocatalytic Fluoroalkylation of 2-Isocyanides with RfSO2Cl as Both a Fluoroalkyl Radical Source and HAT Reagent

The first example of the dual-functional photocatalytic fluoroalkylation of 2-isocyanides with RfSO2Cl catalyzed by Yb@g-C3N4 has been accomplished by simultaneously coupling the photogenerated electron-driven reductive production of fluoroalkyl radicals with the photogenerated hole-driven oxidative production of chloride radicals. This strategy not only fully utilizes photogenerated electron–hole pairs for bond formation but also avoids the use of exogenous chloride salts, additional redox reagents, and sacrificial electron donors/acceptors. A variety of fluoroalkylated N-heteroarenes were heterogeneously synthesized in good to high yields with excellent functional-group compatibility. Furthermore, applying sono-photocatalysis not only improves the energy efficiency but also increases the reaction rate and overall efficiency.