Epidemiology, Prevention, and Clinical Management of Allergic Rhinitis

医学 免疫球蛋白E 过敏 哮喘 免疫学 免疫系统 重症监护医学 公共卫生 免疫病理学 炎症 抗体 梅德林 鼻喷雾剂 过敏性炎症
作者
Vikash Chandra Mishra,R. Babu
出处
期刊:Hormone and Metabolic Research [Thieme Medical Publishers (Germany)]
卷期号:57 (08): 453-463 被引量:1
标识
DOI:10.1055/a-2687-6822
摘要

Allergic rhinitis (AR) is a widespread chronic condition caused by immune responses involving immunoglobulin E (IgE) when exposed to airborne allergens. It frequently coexists with conditions such as asthma and eye inflammation and represents a major public health issue due to its significant burden and associated disabilities across the globe. Key contributing factors include exposure to airborne or workplace-related allergens and hereditary predispositions. AR negatively impacts daily life, including social interactions, academic performance, and productivity at work, while also leading to considerable economic expenses. The ARIA (Allergic Rhinitis and its Impact on Asthma) guidelines categorize AR based on duration (intermittent or persistent) and severity (mild or moderate/severe). Diagnosis primarily relies on clinical evaluation, and in patients with uncontrolled or long-term symptoms, confirmation may involve skin prick testing or detecting specific IgE antibodies in the blood. Common treatments include oral, nasal, or eye-drop antihistamines (H1-blockers), nasal corticosteroids, or a combination of both delivered intranasally. Allergen-specific immunotherapy, administered by qualified specialists and using standardized extracts, is beneficial for individuals with ongoing symptoms. Insights from real-life data collected through mobile applications are enhancing understanding of AR types and their management. Future developments aim to improve recognition of complex overlapping conditions, utilize health technology evaluations, and promote patient-involved treatment decisions.
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