医学
黑色素瘤
前哨淋巴结
解剖(医学)
局部广泛切除术
重症监护医学
哨兵节点
活检
淋巴结
疾病
免疫疗法
外科
皮肤病科
癌症
普通外科
放射科
内科学
乳腺癌
癌症研究
作者
Rebecca I. Hartman,Jennifer Y. Lin
标识
DOI:10.1016/j.hoc.2018.09.005
摘要
Melanoma is an increasingly common cancer in the United States, although mortality has likely stabilized. Diagnosis relies on a skilled practitioner with the aid of dermoscopy and initial local surgical management is a mainstay of treatment. Recent changes in staging emphasize continued use of sentinel lymph node biopsy to aid in prognostication although routine complete lymph node dissection has fallen out of favor. Advances in systemic treatment options, including targeted and immunotherapy, have dramatically changed the treatment paradigm for advanced melanoma and improved outcome. Prevention via sun protection remains a critical tool in efforts to limit the burden of this disease.
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