二面角
喹唑啉
戒指(化学)
化学
结晶学
离子
盐酸盐
立体化学
分子
有机化学
氢键
作者
S. Selvanayagam,B. Sridhar,Κ. Ravikumar
标识
DOI:10.1107/s1600536808011707
摘要
In the cation of the title compound, C(22)H(24)N(3)O(4) (+)·Cl(-), an active ingredient of the anti-cancer drug also known as Tarceva, the quinazoline ring system is planar within 0.044 (3) Å. The dihedral angle formed by the mean planes of the two six-membered quinazoline rings is 3.2 (1)°. Both N-bound H atoms participate in N-H⋯Cl bonds, which link the ions into infinite chains running along the b axis. C-H⋯O inter-actions involving neighboring cations provide additional stabilization of these aggregates.
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