B cell depletion therapy for rheumatoid arthritis

Rheumatoid arthritis(RA)is an autoimmune disease that is well characterized by chronic inflammation in the affected joints and can cause disability.Yet the precise etiology of RA remains unclear,the developments have heen made in the research on its pathogenesis.Recently,B cell depletion therapy has been proved to be efficiency and safety in a clinical trial for RA;the successes of this trial have renewed enthusiasm for the role of B cells in this disease and brought the new light to the patients.