A new monoterpenoid glycoside from roots of Zanthoxylum simulans

Objective To study the chemical constituents from the roots of Zanthoxylum simulans. Methods The constituents were isolated and purified by column chromatography and their structures were identified by physicochemical and spectral data. Results A new monoterpenoid glycoside and four known compounds were isolated from the ethanol extracts in the roots of Z. simulans. Their structures were elucidated as (1R, 2R, 4S)-2-hydroxy-1, 8-cineole-2-O-α-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (Ⅰ), icariside E5(Ⅱ), flindersine (Ⅲ), N-methylflindersine (Ⅳ), and daucosterol (Ⅴ). Conclusion Compound Ⅰ is a new compound named as zansimuloside A. Compound Ⅱ is isolated from the plants of Zanthoxylum L. for the first time.