From the aerial parts of Saxifraga melanocentra,ten compounds were isolated and identified with spectral analysis and compared with authentic samples as kaermpferol (1),quercetin (2),kaempferol-3-O-β-D-glucoside (3),quercetin-3-O-β-D-glucoside (4),kaempferol-3-rutinoside (5),rutin (6),2″-O-galloylrutin (7),bergenin (8),gallic acid (9) and methyl gallate (10).Six compounds were found from the plant for the first time with the exception of 2,6,8 and 10.These results provided new chemical evidences for the bioactive investigation of this plant.