Objective: To compare the clinical effective differences between the three acupuncture method with the purpose ofshrinking stomach,opening lockand only body acupuncture method for the treatment of simple obesity. Methods: 1600 patients were randomly divided into the therapy group of three acupuncture method( n =1 200) and only body acupuncture therapy control group( n = 400). Three acupuncture therapy group was treated with eye needling,the awn needling,body needling for the purpose ofshrinking stomach,opening lock,and acupuncture at Sanjiao region in eye needling; Juquetouhuangsu( RN14) in the awn needling; Tianshu( ST25),Qihai( RN6),taiyi( ST23),etc in body acupuncture. Control group was treated with body needling method only. The therapeutic effects were observed after 10 times in a course of treatment. Results: The total effective rate was 97. 25% in the three acupuncture method group and was 80. 75% in the body acupuncture control group,with a significant difference between the two groups( P 0. 01). Conclusion: Three acupuncture method with the purpose of shrinking stomach,opening lockhas a better therapeutic effect on simple obesity than that of body acupuncture method.