Objective To analyze the immune state of the patients with OLP and to discuss its pathogenesis.Methods Celular immunity and humoral immunity of 32 cases with OLP were detected,the results were analyzed.Results There was an obvious abnormity in the routine index of cellular immunity and humoral immunity of the OLP patients.Conclusions The routine index of cellular immunity and humoral immunity are helpful in judging the immune state of the OLP patients and can be used as a reference in diagnosis and treatment selection.